Journal Publications
Chen TT, Chen CY, Liu CY, Lee J, Ganna A, Feng YCA, Lin YF. Genetic architectures of childhood maltreatment and causal influence of childhood maltreatment on health outcomes in adulthood. Molecular Psychiatry. 2025 Feb.
Lin SC, Lin SH, Ge T, Chen CY, Lin YF. Causal Mediation Analysis: A Summary-Data Mendelian Randomization Approach. Medicine. 2025 Feb; 44:e10317
Wu SG, Ho CC, Yang JC, Yu SH, Lin YF, Lin SC, Liao BC, Yang CY, Lin YT, Yu CJ, Chuang YT, Liao WY, Yap KY, Kou WS, Shih JY. Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR-mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis. Clinical and Translational Medicine. 2025 Jan;15(1):Article number e70149.
Fan HY, Tsai MC, Lai CJ, Yeh CL, Hsu HY, Lai PJ, Hsu HC, Su TC, Lin HJ, Lin YF, Lu TP, Chien KL. Genetic variants in severe hypertriglyceridemia among taiwanese participants - insights from genome-wide association and whole-exome sequencing analyses. Circulation Journal. 2024 Dec 11;Article in Press.
Wu CS, Hsu CL, Lin MC, Su MH, Lin YF, Chen CY, Hsiao PC, Pan YJ, Chen PC, Huang YT, Wang SH. Association of polygenic liabilities for schizophrenia and bipolar disorder with educational attainment and cognitive aging. Transl Psychiatry. 2024 Nov 16;14(1):472.
Wu JY, Tsai YY, Chen YJ, Hsiao FC, Hsu CH, Lin YF, Liao LD. Digital transformation of mental health therapy by integrating digitalized cognitive behavioral therapy and eye movement desensitization and reprocessing. Medical and Biological Engineering and Computing. 2024 Oct 14;Article in Press.
Hsu YC, Su MH, Chen CY, Lin YF, Wang SH. Associations of polygenic risk for depression, traditional Chinese medicine constitution, and depression: A population-based study in Taiwan. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 2024 Sep;Article in Press.
Yuan K, Longchamps RJ, Pardiñas AF, Yu M, Chen TT, Lin SC, Chen Y, Lam M, Liu R, Xia Y, Guo Z, Shi W, Shen C; Schizophrenia Workgroup of Psychiatric Genomics Consortium; Daly MJ, Neale BM, Feng YA, Lin YF, Chen CY, O’Donovan MC, Ge T, Huang H. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. Nature Genetics. 2024 Sep;56(9):1841-1850. (2023 IF=31.7)
Chen TT, Kim J, Lam M, Chuang YF, Chiu YL, Lin SC, Jung SH, Kim B, Kim S, Cho C, Shim I, Park S, Ahn YU, Okbay A, Jang H, Kim HJ, Seo SW, Park WY, Ge T, Huang H, Feng YCA, Lin YF*, Myung W*, Chen CY*, Won HH*. Shared genetic architectures of educational attainment in East Asian and European populations. Nature Human Behaviour. 2024 Mar;8(3):562-575. (2023 IF =21.4)
Lai RY, Su MH, Lin YF, Chen CY, Pan YJ, Hsiao PC, Chen PC, Huang YT, Wu CS, Wang SH. Relationship between mood disorders and substance involvement and the shared genetic liabilities: A population-based study in Taiwan. Journal of Affective Disorders. 2024 Jan 15:345:168-176. (2023 IF =4.9)
Chen CY*, Chen TT, Feng YCA*, Yu M, Lin SC, Longchamps RJ, Wang SH, Hsu YH, Yang HI, Kuo PH, Daly MJ, Chen WJ, Huang H *, Tian Ge T*, Lin YF*. Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits. Cell Genomics. 2023 Dec 13; 3(12): 100436. (2023 IF=11.1)
Campos AI, Namba S, Lin SC, Nam K, Sidorenko J, Wang H, Kamatani Y; Biobank Japan Project; Wang LH, Lee S, Lin YF, Feng YA, Okada Y, Visscher PM, Yengo L. Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores. Nature Genetics, 2023 Oct;55(10):1769-1776. (2023 IF =31.7)
Chiu YW, Su MH, Lin YF, Chen CY, Chen TT, Wang SH. Causal influence of sleeping phenotypes on the risk of coronary artery disease and sudden cardiac arrest: A Mendelian randomization analysis. Sleep Health. 2023 Oct; 9(5):726-732. (2023 IF =5.3)
Huang CY, Lin YF, Chen CR, Lin SK. Post-therapy plasma concentrations of quetiapine in Taiwanese patients. Neuropsychopharmacol Rep. 2023 Jan 16; 43(1):50-56. (2023 IF=2)
Wang, Y., Namba, S., Lopera, E., Kerminen, S., Tsuo, K., Läll, K., … Chen TT, …, Lin YF, … & UCLA ATLAS Community Health Initiative. Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts. Cell Genomics. 2023 Jan 4; 3(1): 100241. (2023 IF=11.1)
Lin, YF, Chou, WH, Liu, TH, Fang, CP, Kuo, HW, Kuo, PH, Tsai, SJ, Wang, SC, Chung, RH, Tsou, HH, Chen, ACH, Liu, YL. Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment. Int J Mol Sci. 2022 Dec 31; 24(1):721. (2022 IF = 5.6)
Liao SF, Su CY, Su MH, Chen CY, Chen CY, Lin YF, Pan YJ, Hsiao PC, Chen PC, Huang YT, Wu CS, Wang SH. Associations of polygenic risks, depression, and obesity-related traits in Taiwan Biobank. J Affect Disord. 2023 Jan 1;320:397-403. (2023 IF =4.9)
Chen TT, Chen CY, Fang CP, Cheng YC, Lin YF*. Causal influence of dietary habits on the risk of major depressive disorder: A diet-wide Mendelian randomization analysis. J Affect Disord. 2022 Dec 15;319:482-489. (2022 IF =6.6)
Kanai M, Elzur R, Zhou W, Wu KHH, Rasheed H, Tsuo, K., … Chen TT, …, Lin YF, … & Biobank of the Americas. Meta-analysis fine-mapping is often miscalibrated at single-variant resolution. Cell Genomics. 2022 Dec 14;2(12): 100210. (2023 IF=11.1)
Feng YCA, Chen CY, Chen TT, Kuo PH, Hsu YH, Yang HI, Chen WJ, Su MW, Chu HW, Shen CY, Ge T, Huang H, Lin YF*. Taiwan Biobank: A rich biomedical research database of the Taiwanese population. Cell Genomics. 2022 Nov 9;2(11):100197. (2023 IF=11.1)
Zhou W et al. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. Cell Genomics. 2022 Oct 12;2(10):100192. (2023 IF=11.1)
Su MH, Lai RY, Lin YF, Chen CY, Feng YA, Hsiao PC, Wang SH. Evaluation of the causal relationship between smoking and schizophrenia in East Asia. Schizophrenia (Heidelb). 2022 Sep 9;8(1):72. (2022 IF =5.4)
Wang SH, Su MH, Chen CY, Lin YF, Feng YCA, Hsiao PC, Pan YJ, Wu CS. Causality of abdominal obesity on cognition: a trans-ethnic Mendelian randomization study. Int J Obes (Lond). 2022 Aug;46(8):1487-1492. (2022 IF =4.9)
Ge T, Irvin MR, Patki A, Srinivasasainagendra V, Lin YF, Tiwari HK, Armstrong ND, Benoit B, Chen CY, Choi KW, Cimino JJ, Davis BH, Dikilitas O, Etheridge B, Feng YA, Gainer V, Huang H, Jarvik GP, Kachulis C, Kenny EE, Khan A, Kiryluk K, Kottyan L, Kullo IJ, Lange C, Lennon N, Leong A, Malolepsza E, Miles AD, Murphy S, Namjou B, Narayan R, O’Connor MJ, Pacheco JA, Perez E, Rasmussen-Torvik LJ, Rosenthal EA, Schaid D, Stamou M, Udler MS, Wei WQ, Weiss ST, Ng MCY, Smoller JW, Lebo MS, Meigs JB, Limdi NA, Karlson EW. Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Med. 2022 Jun 29;14(1):70. (2022 IF =12.3)
Ruan Y, Lin YF, Feng YCA, Chen CY, Lam M, Guo Z, Stanley Global Asia Initiatives, He L, Sawa A, Martin AR, Qin S, Huang H, Ge T. Improving polygenic prediction in ancestrally diverse populations. Nat Genet. 2022 Aug;54(8):1259. (2022 IF =30.8)
Su MH, Shih YH, Lin YF, Chen PC, Chen CY, Hsiao PC, Pan YJ, Liu YL, Tsai SJ, Kuo PH, Wu CS, Huang YT, Wang SH. Familial aggregation and shared genetic loading for major psychiatric disorders and type 2 diabetes. Diabetologia. 2022 May;65(5):800-810. (2022 IF = 8.2)
Lin YF, Chen PY, Liu HC, Chen YL, Chou WH, Huang MC*. Shortened Leukocyte Telomere Length in Young Adults Who Use Methamphetamine. Transl Psychiatry. 2021 Oct 9;11(1):519. (2021 IF = 7.989)
Chou PH#, Lin YF#, Lu MK, Chang HA, Chu CS, Chang WH, Kishimoto T, Sack AT, Su KP. Personalization of repetitive transcranial magnetic stimulation for the treatment of major depressive disorder according to the existing psychiatric comorbidity. Clin Psychopharmacol Neurosci. 2021; 19(2): 190-205 (#equal contribution as co-first authors) (2021 IF = 3.731)
Lin YF*. Methodology in the GBD study of China. Lancet. 2020 Jul;396(10243):25-26. (2020 IF = 79.323)
Lin YF, Smith AV, Aspelund T, Betensky RA,Smoller JW, Gudnason V, Launer LJ, BlackerD*. Genetic overlap between vascular pathologies and Alzheimer’s dementia and potential causal mechanisms. Alzheimer’s Dement. 2019 Jane; 15(1):65-75. (IF=21.566)
Lin SK*, Lin YF, Yang SY, He YL, Kato TA, Hayakawa K, Park Y, Sim K, Chiu HFK, Xiang Y, Chong MY, Tan CH, Inada T, Shinfuku N. Comparison of the defined daily dose and chlorpromazine equivalent methods in antipsychotic drug utilization in six Asian countries. Neuropsychiatry (London). 2018 December; 8(6), 1847–1852.
Lin YF*(correspondence), Chen CY, Öngür D, Betensky R, Smoller JW, Blacker D, Hall MH. Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms. Transl Psychiatry. 2018 May 16; 8(1):97. (IF=6.222)
Chang YS, Trivedi MK, Jha A, Lin YF, Dimaano L, García-Romero MT*. Synbiotics for prevention and treatment of atopic Dermatitis: a meta-analysis of randomized clinical trials. JAMA Pediatr. 2016 March 1; 170(3):236-242. (IF=16.193)
Lin YF, Huang MC, Liu HC*. Glycogen Synthase Kinase 3β gene polymorphisms may be associated with bipolar I disorder and its response to lithium treatment. J Affect Disord. 2013 May; 147(1-3):401-406. (IF=4.839)
Wang SC, Tsou HH, Chen CH, Chen YT, Ho IK, Hsiao CF, Chou SY, Lin YF, Fang KC, Huang CL, Su LW, Fang YC, Liu ML, Wu HY, Lin KM, Liu SC, Kuo HW, Chiang IC, Chen ACH, Tian JN, Liu YL*. Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients. Eur Neuropsychopharmacol. 2012 October; 22(10):695-703. (IF=4.600)
Chen CH, Wang SC, Tsou HH, Ho IK, Tian JN, Yu CJ, Hsiao CF, Chou SY, Lin YF, Fang KC, Huang CL, Su LW, Fang YC, Liu ML, Lin KM, Hsu YT, Liu SC, Chen ACH, Liu YL*. Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients. Pharmacogenomics. 2011 October; 12(10):1397-406. (IF=3.550)
Book Chapters
Chung AN, Chen TT, Lin YF*. Genetics of Antidepressant Response and Treatment Resistant Depression. In: Treatment-Resistant Depression, Progress in Brain Research. Volume 278. 2023 Elsevier. ISBN: 9780323957786. (https://doi.org/10.1016/bs.pbr.2023.01.002)